游一龍（Lung Yu）特聘教授

Education and Career Experience：

National Taiwan University (B.S.)，1983-1987

National Taiwan University (M.S.)，1987-1989

Rutgers University (Ph.D.)，1992-1996

Yale University (Post Doctoral fellow)，1996-1997

Institute of Behavioral Medicine, Assistant Professor，1997-2002

Institute of Behavioral Medicine, Associate Professor，2002-2005

Institute of Behavioral Medicine, Professor，2005- 2011

Institute of Behavioral Medicine, Distinguished Professor，2012- 2016

Department of Physiology, Distinguished Professor，2017-

Speciality ：

Substance abuse and neurotoxicity study, Social neuroscience、learning and memory

Awards ：

Dr. Ta-You Wu Memorial Award from NSC in Taiwan, 2002

Award for Excellence in Research from NSC in Taiwan, 2012

Award for Excellence in Teaching from NCKU, 2007; 2010

Award for an Excellent Article for the year from Cheng-Shin Medical Education Foundation, 2008, 2015

Award for NCKU Faculty of Excellence from NSC in Taiwan, 2013

…

E-mail

lungyu@mail.ncku.edu.tw

Office

Extention：5106, 5455

Laboratory

EXT：5434, 5042

Hobby：

Research Interests：

1.Mechanisms underlying MA- , MDMA-, ketamine-, and polydrug-induced neurotoxicity

2.Roles of the signaling pathways in modulating cocaine-associated memory and drug abstinence

3.Sex differences in neurodegenerative diseases, substance abuse, and emotion-related mental disorders

4.Stress, aging and immune system

5.Social neurosciences (social support, conformity, learned helplessness, psychological fatigue)

Lab Members：

Current

Postdoctoral Fellow: Vivi Tzeng, Ph.D. major in Behavioral Neuroscience

Pursuing M.S.: Yaya Wang (B.S. major in Biological Medical Sciences), Jill Sun (B.S. major in Life Science), Alice Song (B.S. major in Bioscience), Ryan Chang (B.S. major in Marine Science?)

Research Associates (Sei Chang Chien, Heidi Deng)

Alumni:

Too many to be listed, will be updated in case they request for being enlisted!

Publications（PubMed）

Publications for the latest five years since 2012

1.Tzeng, W-Y., Chang, W-T., Lin, K-Y., Cherng, C.G., Yu, L. (Correspondence Author), 2012, Reactivation of a memory affects reconsolidation of other, non-reactivated memory. Neurobiol Learn Mem, 97: 241-249.

2.Cherng, C.G., Chang, C.P., Su, C-C., Chuang, C-J., Tzeng, W-Y., Chen, L-H., Lin, K-Y., Yu, L. (Correspondence Author), 2012, Odors from proximal species reverse the stress-decreased neurogenesis via main olfactory processing. Behav Brain Res, 229:106-112.

3.Hsu Y-C., Yu L., Chen H-I., Lee H-L., Kuo Y-M., Jen C. J., 2012, Blood pressure variations real-time reflect the conditioned fear learning and memory. PLoS One, 7(4):e32855.

4.Chuang, J-Y., Lin, K-Y., Cherng, C.G., Yu, L. (Correspondence Author), 2012, Anisomycin interrupted the reconsolidation of the reactivated memory. Chin J Physiology, 55: 314-322.

5.Chuang J-Y., Lee C-W., Shih Y-H., Yang T., Yu L. (Correspondence Author), Kuo, Y-M., 2012, Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease. PLoS One, 7(3):e33120.

6.Kao, G-S., Cheng, L-Y., Chen L-H., Tzeng W-Y., Cherng, C.G., Su C-C., Wang, C-Y., Yu, L. (Correspondence Author), 2012, Neonatal isolation decreases cued fear conditioning and frontal cortical histone 3 lysine 9 methylation in adult female rats. Eur J Pharm, 697: 65-72.

7.Huang, T-Y., Lin, L-S., Cho, K-C., Chen, S-J., Kuo, Y-M., Yu, L., Wu, F-S., Chuang, J-I., Chen, H.I., Jen C., 2012, Chronic treadmill exercise in rats delicately alters the Purkinje cell structure to improve motor performance and toxin resistance in the cerebellum. J Appl Physiol, 113: 889-895

8.Lu, T-J., Lu, R-B., Hong, J-S., Yang, Y. K., and Yu, L. (Correspondence Author), 2013, An electroconvulsive stimulus impairs reconsolidation of pavlovian conditionings. Chin J Physiol, 56: 44-51.

9.Tzeng, W-Y., Chuang, J-Y., Lin, L-C., Cherng, C.G., Su C-C., Chen, L-H., and Yu, L. (Correspondence Author), 2013, Companions reverse stress-induced decreases in neurogenesis and cocaine conditioning possibly by restoring BDNF and NGF expression in dentate gyrus. Psychoneuroendocrinol, 38, 425-437.

10.Yang, F-Y., Lee, Y-S., Cherng, C.G., Chang, W-T., Chuang, J-Y., Kao G-S., Yu, L. (Correspondence Author), 2013, Sarcosine and D-serine facilitate the extinction of cocaine-induced conditioned place preference memory. J Psychopharm, 27: 550-558.

11.Chen, M-F., Huang, T-Y., Kuo, Y-M., Yu, L., Chen, H., Jen, C. J., 2013, Early postinjury exercise reverses memory deficits and retards the progression of closed-head injury in mice. J Physiol, 591: 985-1000.

12.Wen-Yu Tzeng, Li-Shen Chen, Chianfang G. Cherng, Yi-Ni Tsai, and Lung Yu (Correspondence Author). 2014, Sex differences and the modulating effects of gonadal hormones on basal and the stressor-decreased newly proliferative cells and neuroblasts in dentate gyrus. Psychoneuroendocrinol, 42: 24-37.

13.Cherng, C.G., Wang, C-Y., Lai, Y-T., Tzeng, W-Y., Chen, L-S., Tsai, Y-N., Yu, L. (Correspondence Author). 2014, Anticipated intense risk enhances behavioral conformity in a mouse model. Ethology, 120: 1035-1043.

14.Chen, L-S., Tzeng, W-Y, Chuang, C-Y., Cherng, C.G., Gean, P-W., Yu, L. (Correspondence Author), 2014, Sex differences in cued fear conditioning and LTP induction in mouse lateral nucleus of amygdala. Horm Behav, 66: 498-508.

15.S-F. Tsai, T-Y. Huang, C-Y. Chang, Y-C. Hsu, S-J. Chen, L. Yu, Y-M. Kuo, C.J. Jen. Social instability stress differentially affects amygdalar neuron adaptations and memory performance in adolescent and adult rats. Front. Behav. Neurosci. 2014, doi: 10.3389/fnbeh.2014.00027.

16. Y-H. Tsou, C-T. Shih, C-H. Ching, J-Y. Huang, C.J. Jen, L. Yu, Y-M. Kuo, F-S. Wu, J-I. Chuang, 2015, Treadmill exercise activates Nrf2 antioxidant system to protect the nigrostriatal dopaminergic neurons from MPP+ toxicity. Exper Neurol 263: 50-62.

17.Y-N. Tsai, W-Y. Tzeng, C.G. Cherng, T.Y. Liao, H-H. Wu, J-K. Lin, L. Yu. (Correspondence Author), 2016, Sodium benzoate combined with extinction training and the facilitated extinction of cocaine-supported memory. Chin J Physiol, 59: 56-61.

18.S.S-J. Hu, Y-W. Liu, L.Yu, (Correspondence Author), 2015, Medial prefrontal cannabinoid CB1 receptors modulate consolidation and extinction of cocaine-associated memory in mice. Psychopharm, 232: 1803-1815.

19.T.Y. Liao, W-Y. Tzeng, H-H. Wu, C.G. Cherng, J-K. Lin, S-J. S. Hu, L. Yu (Correspondence Author), 2016, Rottlerin impairs the formation and maintenance of psychostimulant-supported memory. Psychopharm, 233: 1455-1465.

20.Y-C. Hsu, S-F. Tsai, L. Yu, J-I. Chuang, F-S. Wu, C.J. Jen, Y-M. Kuo, 2015, Long-termmoderate exercise accelerates the recovery of stress-evoked cardiovascular responses. Stress, DOI: 10.3109/10253890.2015.1108305

21.T-W. Lin, Y-F. Liu, Y-H. Shih, S-J. Chen, T-Y. Huang, C-Y. Chang, C-H. Lien, L. Yu, S-H. Chen and Y-M. Kuo, 2016, Neurodegeneration in amygdala precedes hippocampus in the APPswe/PS1dE9 mouse model of Alzheimer’s disease. Curr Alzhei Res, 12: 951-963.

22. Y-N. Tsai, W-Y. Tzeng, C.G. Cherng, T.Y. Liao, H-H. Wu, J-K. Lin, L. Yu. (Correspondence Author), 2016, Sodium benzoate combined with extinction training and the facilitated extinction of cocaine-supported memory. Chin J Physiol, 59: 56-61.

23.T-Y. Liao, W-Y. Tzeng, H-H. Wu, C.G. Cherng, C-Y. Wang, SS.J. Hu, L. Yu (Correspondence Author), 2016, Rottlerin impairs the formation and maintenance of psychostimulant-supported memory. Psychopharm, 233: 1455-1465.

24.W-Y. Tzeng, C.G. Cherng, S-W. Wang, L. Yu (Correspondence Author), 2016, Familiar companions diminishes cocaine conditioning and attenuates cocaine-stimulated dopamine release in the nucleus accumbens. Behav Brain Res, 306:146-153.

25.L-W. Tung, G-L. Lu, Y-H. Lee, L. Yu, H-J. Lee, H. Bradshaw, L-L. Hwang, M-S. Hung, K. Mackie, A. Zimmer, L-C. Chiou, 2016, Orexins disinhibit dopamine neurons via endocannabinoids contributing to restraint stress-induced cocaine relapse. Nature Comm, 7:12199.

26.W-Y. Tzeng, C-F.G. Cherng, L. Yu (Correspondence Author), and C-Y. Wang, 2016, Involvement of amygdalar D2 receptor activation in companions’ dampening effect on cocaine conditioning. Neurobiol Learn Mem, 137:48-55.

27.W-Y. Tzeng, H-H. Wu, J-C. Chen, L. Yu (Correspondence Author), and C.G. Cherng, 2017, Sex differences in stress and group housing effects on the number of newly proliferated cells and neuroblasts in middle-aged dentate gyrus. Front Behav Neurosci, 10:249.

書及教科書(Books and Textbooks)

1.細說研究:一條尋幽訪勝的臨淵小境 與程千芳合著 (2014), 雙葉, 臺北, 中華民國

2.老年心理學:從心理科學看成功老化 與程千芳合著 (2015), 雙葉, 臺北, 中華民國

3.普通心理學 第二版 與程千芳合著 (2015), 華杏, 臺北, 中華民國

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