Alice Y.W. Chang
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Alice Y.W. Chang, Professor |
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Education and Experience: B.S. Taipei Medical University, 1984-1988 M.S. National Yang Ming University, 1991-1993 PhD. National Yang Ming University, 1993-1998 Assistant Professor, National Sun Yat-sen University, 1998-2001 Associate Professor, National Sun Yat-sen University, 2001-2005 Professor, National Sun Yat-sen University, 2005-2009 Principle Investigator, Chang Gung Memorial Hospital, 2009-2014 Joined Professor, National Sun Yat-sen University, 2009- Joined Professor, Kaohsiung Medical University, 2010-2015 Professor, National Cheng Kung University, 2014- |
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Speciality: Pharmacology, Neuroscience, Toxicology, Circulatory physiology, Brain damage
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Award: 1999-2001: Research Achievement Award, National Science Council, Taiwan 2001：Young Investigator Award, National Sun Yat-sen University, Taiwan 2006：Outstanding Research Award, Pharmacological Society in Taiwan, Taiwan 2007：Research Excellence Award, National Sun Yat-sen University, Taiwan 2008：Outstanding Senior Teacher, National Sun Yat-sen University, Taiwan 2009-2014：Research Award, Chang Gung Memorial Foundation
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aywchang@mail.ncku.edu.tw |
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Office |
82-0730 ext. 5445 |
Laboratory |
82-0740 ext. 5445 |
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Hobbies: happy life |
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Research interests： |
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1. Investigate the mechanisms organophosphate poisoning and its potential antidote 2. Dissect the dysfunction and dysregulation of central nervous system in cardiovascular and neurological consequences after stroke 3. Study the mechanisms of epilepsy-induced damage responses 4. Demonstrate the mechanisms of fatal drug addiction 5. Examine the important interaction between neurons and glia in neurological diseases 6. Determine the epigenetic mechanisms of esophageal squamous-cell carcinoma |
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People: |
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Current member Postdoc: Li, F.C.H. Ph.D students: Yuen, C.M. (1st year), Tsai, S.T. (1st year) Ms.D students: Chiu, C.M. (1st year), Chen, T.E. (1st year), Hung, Y.T. (1st year)
Former member |
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Publication list（PubMed Lik） |
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1. Chan SHH, Chan JYH, Hsu KS, Li FCH, Sun EYH, Chen WL, **Chang AYW. Amelioration of central cardiovascular regulatory dysfunction by tropomyocin receptor kinase B in mevinphos intoxication model of brain stem death. British Journal of Pharmacology. 2011;164:2015-28. 2. Li FCH, Yen JC, Chan SHH, **Chang AYW. Bioenergetics failure and oxidative stress in brain stem mediates cardiovascular collapse associated with fatal methamphetamine intoxication. PLoS One. 2012;7:e30589. 3. Li FCH, Li BPT, Wu JY, Wu JCC, **Chang AYW. Transition from oxidative stress to nitrosative stress in rostral ventrolateral medulla underlies fatal intoxication induced by organophosphate mevinphos. Toxicological Sciences. 2013;135:202-17. 4. **Chang AYW, Li FCH, Huang CW, Wu JCC, Dai KY, Chen CH, Li SH, Su CH, Wu RW. Interplay between brain stem angiotensins and monocyte chemoattractant protein-1 as a novel mechanism for pressor response after ischemic stroke. Neurobiology of Diseases. 2014;71:292-304. 5. Huang CW, Tsai MH, Chen NC, Chen WH, Lu YT, Lui CC, Chang YT, Chang WN, **Chang AYW, Chang CC. Clinical significance of circulating vascular cell adhesion molecule-1 to white matter disintegrity in Alzheimer's dementia. Thrombosis and Haemostasis. 2015;114:1230-40. 6. Chen YH, Huang CH, Lu HI, Chen CH, Huang WT, Hsieh MJ, Rau KM, Chang AYW, Lin WC, Li SH. Prognostic impact of renin-angiotensin system blockade in esophageal squamous cell carcinoma. Journal of Renin Angiotensin Aldosterone System. 2015;16:1185-92. |
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Laboratory View |
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Laboratory activities |
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